An ethics primer for nurses and nursing students that advances a vision for a holistic Christian notion of health and explores what Christian faith means, on a practical level, for the practice of nursing.

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Excerpt from The Appeal to Immediate Experience: Philosophic Method in Bradley Whitehead and Dewey The insight and guidance of Professor John Herman Randall, Jr. have made this book possible. Rather than merely acknowledge my debt to him I would like to express my gratitude here for his unfailing kindness, his penetrating criticism of my efforts, and the help he has given me in clarifying the complex problems of this subject-matter. I wish also to acknowledge the kindness of the following publishers (...) in permitting me to quote from their publications: F. H. Bradley, Appearance and Reality, by Allen and Unwin Ltd.; J. H. Randall, Jr. and J. Buchler, Philosophy: An Introduction, by Barnes Noble, Inc.; F. H. Bradley, Appearance and Reality and Essays on Truth and Reality, by Clarendon Press, Oxford; F. J. E. Woodbridge, Nature and Mind, by Columbia University Press; R. W. Church, Bradley's Dialectic, by Cornell University Press; John Dewey, The Man and His Philosophy, by Harvard University Press; J. Dewey, Logic and Influence of Darwin on Philosophy, by Henry Holt Company; R. Kagey, F. H. Bradley's Logic, by R. Kagey; J. Dewey, Nature in Experience and Whitehead's Philosophy, by Longmans, Green & Co.; A. N. Whitehead, Symbolism, Modes of Thought, Adventures of Ideas, Process and Reality, T. M. Forsyth, English Philosophy, and J. H. Muirhead, Bradley's Place in Philosophy, by the Macmillan Company; A. N. Whitehead, The Concept of Nature-and An Equiry Concerning the Principles of Natural Knowledge, by the Macmillan Company and the Cambridge University Press; H. B. Haldane, Human Experience, by John Murray Ltd.; J. Goheen, Whitehead's Theory of Value, by Northwestern University Press; J. Dewey, Experience and Nature, by Open Court Publishing Co.; G. Santayana, Realm of Essence and Scepticism and Animal Faith, by Charles Scribner's Sons; and J. Dewey, "How is Mind to be Known?" The Objectivism-Subjectivism of Modern Philosophy," M. Gross, The Philosophy of A. N. Whitehead," and M. C. Otto, The Journal of Philosophy. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

In “A Short Refutation of Ethical Egoism,” Richmond Campbell purports to refute “the view that everyone ought to do what benefits him the most in a given situation.” This is the theory which is “sometimes called impersonal ethical egoism ” [249). Campbell takes the following proposition as fundamental to his refutation of IEE.I. If an agent ought to do something in a given situation and another agent ought to do something in the same situation, then it is not logically impossible (...) for them to do these things in that situation [250].Granted proposition I, Campbell's refutation would require only:II. There is a situation S where an agent M would benefit most from doing X and another agent N would benefit most from doing what would prevent M from doing X [251]. (shrink)

Each year since 1983 the American Council of Learned Societies has invited one of America's leading scholars to deliver the Haskins Lecture, in honor of Charles Homer Haskins, a distinguished scholar and teacher who was instrumental in the founding of the ACLS. In this volume, which commemorates the 75th anniversary of the ACLS, Douglas Greenberg and Stanley Katz bring together the lectures presented by ten of America's most distinguished scholars. Each lecture is a personal and intellectual glimpse into the "life (...) of learning" of such leading scholars as Maynard Mack, Annemarie Schimmel, and John Hope Franklin. The lectures focus on self-reflection of lives dedicated to learning, rather than on scholarship in the usual sense of the term. Ranging from being forced to learn Latin to painful memories of war and racism, the lecturers all recount stories from their eventful lives. Each offers thoughts on the body of work he or she has produced and the forces, personal and intellectual, that have shaped it. The scholars bring something of their disciplines to the lecture, sharing not only personal anecdotes but their love of learning. (shrink)

Diversity from the beginning: A comparison of Mack and Crossan’s constructs of earliest Christianities (ca 30-70 CE) According to recent propositions by Burton Mack and Dominic Crossan, earliest Christianity was a diverse phenomenon right from its inception. In this article their constructs of this early phase of 'church ’ history (ca 30-70 CE) are compared, so as to identify similarities and differences, advantages and shortcomings. The essay concludes with a proposal on methodological procedure to be followed in the (...) search for earliest forms of Christianities (ca 30-70 CE), as well as some remarks on the meaning of the comparative analysis undertaken by Mack and Crossan. (shrink)

Fruto de una convergencia de motivos e intereses procedentes de diversas disciplinas, los estudios sobre la argumentación han adquirido sus propias señas de identidad como conocimiento, análisis y evaluación del discurso argumentativo a través de sus dimensiones o proyecciones lógica, dialéctica, retórica y socio-institucional. La presente obra trata de reunir, precisar y articular las nociones básicas y los conceptos determinantes de los desarrollos que hoy tienen lugar en ese campo. Este Compendio de lógica, argumentación y retórica se ofrece como una (...) obra de referencia, una herramienta de trabajo y un estímulo para los estudiantes de —y los interesados o los preocupados por— la argumentación, tanto en el plano internacional como, primordialmente, en el medio cultural hispánico e hispanoamericano. No existía hasta ahora una publicación de estas características, a pesar de su necesidad tanto desde el punto de vista didáctico, y en atención a intereses prácticos, como desde el punto de vista teórico. Su elaboración ha ocupado a 59 autores, especialistas y estudiosos de diversos medios académicos y nacionalidades, en la confección de las 176 entradas de las que consta. (shrink)

"--Brian Greene, Columbia University "This book includes material that is intellectually innovative and comes as a surprise even to specialists in the field.

qism 1. Fī al-qānūn. al-Ṭabʻah 5., mazīdah wa-munaqqaḥah wafqan lil-qawānīn al-jadīdah, 1966 -- qism 2. Fī al-ḥuqūq. al-Ṭabʻah 4., mazīdah wa-munaqqaḥah wafqan lil-qawānīn al-jadīdah, 1961.

Ravelingien et al1 argue that, given the restrictions that must be imposed on recipients of xenotransplanted organs, we should conduct clinical trials of xenotransplantation only on patients in a persistent vegetative state. I argue that there is no ethical barrier to using terminally ill patients instead. Such patients can choose to waive their rights to the liberties that xenotransplantation would probably restrict; it is surely rational to prefer to waive your rights rather than to die, and permissible to allow patients (...) to make this choice.Perhaps the single most important advance in the history of moral thought occurred when it came to be generally recognised that all people are protected by rights that are inviolable, at least without their consent. The precise nature and content of these rights is controversial, but there is a consensus among reasonable people over their core. We all have a right to life, to liberty, to security of person and to equality before the law. Other rights—so-called positive rights, such as the right to economic security, or cultural rights, for instance—may be controversial, but we all agree at least on these.Ravelingien et al1 therefore seem to be on solid ground when they conclude that it would not be permissible to use living persons as subjects in clinical trials of xenotransplantation, as such trials, potentially or actually, result in the violation of the core human rights of the subjects. Their argument is as follows:" Xenotransplantation carries with it a currently unquantifiable risk of the transmission of viruses, from the animal that is the source of the organ transplanted, to the human recipient. Such viruses could have potentially catastrophic consequences, up to and including triggering a global and devastating pandemic. Therefore, it would be necessary to monitor the health status of recipients of … ". (shrink)

Fifteen distinguished contributors free present up-to-date arguments for the libertarian alternative. Part One introduces libertarianism and outlines some approaches by which it might be justified. Part Two addresses how a society that embraces libertarian principles might deal with various social problems, especially those that seem to require government intervention. Part Three responds to criticisms of libertarianism from other political perspectives and presents a libertarian critique of those viewpoints. Contributors: N. Scott Arnold; James E. Chesher; Mike Gemmell; John Hospers; Gregory R. (...) Johnson; Loren E. Lomasky; Tibor R. Machan; Eric Mack; Jan Narveson; Douglas B. Rasmussen; Daniel Shapiro; Aeon Skoble; Mark Thornton; Douglas J. Den Uyl; Steven Yates. (shrink)

Die Herrschaft des Behaviorismus in der Psychologie ist gebrochen! Das ist die Ausgangsthese dieses Buches, die im Rahmen des Modells revolutionärer Wissenschaftsentwicklung (Kuhn) als Behauptung eines Paradigmawechsels präzisiert wird. Die Argumentation beschränkt sich nicht nur auf den Nachweis des Niedergangs des Behaviorismus, sondern gibt auch konstruktiv das mögliche neue Paradigma an: als Psychologie des reflexiven Subjekts, das wie der Wissenschaftler (subjektive) Theorien aufstellt, überprüft, bewertet. Der Aufriss einer solchen Psychologie des epistemischen Subjekts unter allgemein-, sozial-, pädagogisch- und klinisch-psychologischem Aspekt thematisiert (...) vor allem: die Rationalität der Reflexionen, Normenkritik und -begründung im Austausch von wissenschaftlichen und naiven Theorien sowie die Berücksichtigung von Reflexivität in der therapeutischen Praxis. Die Rückwendung dieser pychologisch-metatheoretischen Perspektiven auf die Wissenschaftstheorie führt auch zu einer neu. (shrink)

Biodiversity and Conservation 4: 916-928.

The article considers modern transformations of the ideas concerning subject’s cognitive abilities towards object because of the emergence and development of artificial intelligence (AI) technologies. The developments of scientists and engineers from National Research University of Electronic Technology (Moscow, Russia) in the field of artificial intelligence have been taken as a foundation and material of this research. Their analysis allows making a conclusion that the humanity is rather far from the realization of ‘strong artificial intelligence’. We need a qualitative breakthrough (...) in AI material and technological basis for it. Applying ‘model-dependent realism’ by S. Hawking in the course of the speculations in the article, the author concludes that the purpose of cognition in modern science is not to describe an objective reality, but to organize its subjective perception by some definite way. So, the purpose of cognition is the perfection of cognition models permitting a subject ‘to capture’ the reality. This idea is completely confirmed by Maturana and Varela’s autopoiesis theory and von Foerster’s ‘second-order cybernetics’. The article drafts some prospects of moving away from post-nonclassical scientific thinking in its current understanding, because the development of AI technologies results in ‘blurring’ borders of subjectivity in the cognition process. The author concludes that the modern world is moving in another epistemological paradigm where a new scientific revolution is inevitable. (shrink)